Sexually Transmitted Infections (STIs)
As the world descends into chaos, the group of friends barricades themselves inside James' mansion, hoping to wait out the disaster. However, they soon discover that they are not alone. Other celebrities, including Emma Watson, Channing Tatum, and Paul Rudd, seek refuge in the mansion.
As the party gets underway, strange and unexplained events begin to occur. A series of biblical plagues, including locusts, frogs, and hail, start to ravage the city. The guests soon realize that the apocalypse has begun.
As the days pass, the group faces numerous challenges, including marauders, wild animals, and natural disasters. They also discover that the apocalypse is not just a random event, but a biblical prophecy that is unfolding before their eyes.
The movie begins with Jay Baruchel (Seth Rogen), a Canadian actor, arriving in Los Angeles to visit his friend James Franco. James is throwing a party at his new mansion, and Jay is invited along with other celebrities, including Jonah Hill, Craig Robinson, and Rihanna.